Lung cancer occurs when cancer-causing agents cause cells in the lungs to grow abnormally. In most cases, the trigger is cigarette smoke, but non-smokers also develop the disease. Unfortunately, lung cancer has a poor prognosis because it is often discovered late. For patients with metastases to the synovial tissue, the prognosis can be “terrible”.
According to several health authorities, knee pain can occur if the tumor metastasizes or spreads to areas of connective tissue.
In addition, knee pain can result from unusual complications of lung cancer, such as tumor syndromes.
Lung cancer is often detected in the late stages of the disease due to the lack of symptoms at the beginning.
This means that in many cases the tumor has spread to adjacent tissues by the time the diagnosis is made.
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In lung cancer, metastases most often affect the brain, lymph nodes, liver, and adrenal glands, but can spread to almost any part of the body, including synovial tissue.
“Lung carcinoma is the most common primary malignant neoplasm with metastases to synovial tissue, and the knee joint is the most commonly affected joint,” note researchers from the Baylor University Medical Center Records Archive.
Generally speaking, synovial tissue is a type of connective tissue in proactive membranes that surround the joints of the body.
When the knee is affected by a metastatic tumor, symptoms include:
- Decreased ability to stand
- Impaired ability to extend the knee.
These symptoms are sometimes seen in large cell lung cancer, which accounts for 5 to 10 percent of all lung cancers.
“This is a diagnosis of exclusion, as it is often a diagnosis in which a malignant lung tumor does not have the characteristics of olfactory cells, squamous cells, or adenocarcinoma,” scientists at Baylor University Medical Center’s Proceedings Archive explain.
“Most cases of synovial metastasis, especially to the knee joint, from the lung initially showed signs of adenocarcinoma. […] followed by signs of squamous cell carcinoma.
“Unfortunately, all synovial metastases have a terrible prognosis. The median survival after detection is five months.”
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How long does it take for lung cancer symptoms to appear?
It is important to note that some patients with lung cancer live with the tumor for many years before it begins to show obvious signs.
However, once the cells get out of control, they grow into a tumor that destroys nearby areas of the lung.
“Eventually, tumor cells can spread to nearby lymph nodes and other parts of the body,” explains Harvard Health.
According to Medicine Net, squamous cell carcinoma can take about eight years to reach a size of 30 mm, when it is most commonly diagnosed.
At this stage, the most common symptoms are usually a cough, which can be persistent or recurring frequently.
Patients often experience other breathing complications, including persistent shortness of breath or pain and pain when breathing.
As with almost any cancer, early detection is the key to survival.
In patients with small, early-stage lung cancer, the cure rate can be as high as 80-90 percent, according to Cancer Net.