Male pattern baldness or androgenetic alopecia is the most common form of hair loss in men. Two-thirds of men under the age of 35 have noticeable hair thinning. 25% of men who suffer from hereditary baldness face hair loss even before they turn 21 years old.
Contrary to social belief, most men with hair loss are extremely unhappy with their situation and would do anything to change it. Hair loss affects every aspect of their life, affecting their interpersonal relationships as well as their professional life.
Testosterone is often blamed for hair loss. But is it really so?
Dr. Elena Arsova, a trichologist from 101 Hair Clinic says that male sex hormones do play a role in hair loss, but testosterone is not actually the cause of hair loss. Androgens are steroid hormones whose primary function is to maintain male characteristics in humans. The most important androgen is testosterone, which is present in large amounts in men and in small amounts in women. In order to understand the role of testosterone in the androgenetic form of hair loss, it is necessary to understand its metabolism, adds Dr. Arsova.
Testosterone is metabolized into 2 very important hormones: estradiol and DHT (dihydrotestosterone). The enzyme that converts testosterone to DHT is 5 alpha reductase and represents the final step in testosterone metabolism. DHT is a much stronger form of testosterone itself, and is actually responsible for the androgenic type of hair loss. In order to manifest its effect, it is necessary that the hair follicles are sensitive to its effect, which is genetically predisposed.
Hair loss genes that are inherited from both mother and father determine hair follicles to be highly sensitive to androgens, primarily DHT. DHT has 3 times more affinity for androgen receptors that are present in hair follicles. Only in genetically susceptible hair follicles does DHT cause the growth phase of the hair to become shorter. The hairs produced by such follicles cannot grow to their full size due to that short period, so they decrease in size (in length and thickness), a process called miniaturization. Instead of strong and healthy hair, it grows thin and weak instead, so the density and volume of the hair gradually decreases.
Knowing the mechanism of the occurrence of androgenetic hair loss, made it possible to develop methods that successfully treat it. Treatments are based on preventing the action of DHT as well as stimulating follicle function. There are several approved and scientifically proven effective treatments in stopping hair loss and restoring hair growth that are successfully applied all over the world.
Laser biostimulation ensures the growth and replication of hair root cells and maintains hair growth by counteracting the effects caused by DHT. Microneedling mesotherapy works through the formation of small point micropunctures, scars on the skin. During the regeneration process, various active ingredients are released, including hair growth factors that directly improve the function of the follicle, and the stem cells in the hair bulb are also stimulated for better growth.
FUE hair transplantation is a method that enables the transplantation of micrografts from the donor region in thinning zones and ensures not only optimal density but above all a natural appearance of the transplanted hair.