A smelly sign that can signal hypothyroidism compromises the nervous system.

The thyroid gland is a butterfly-shaped gland located above the collarbone and regulates the production of the necessary hormones. Its role is central to several basic bodily functions, including heartbeat, respiration, and metabolism. If its functioning is disturbed, the nervous system can suffer, causing changes in the perception of smells by a person.

Some of the bodily changes associated with a poor thyroid condition occur in the nasal cavity.

The JAMA Network has previously stated, “The connection between the thyroid and the nasal cavity is real, not just a coincidence.

“[It] repeatedly confirmed by various investigators,” the report says.

According to the American Academy of Dermatological Association, people with thyroid problems may notice physical changes in the appearance of their nose, which may become enlarged.

READ MORE: Vitamin deficiencies and hypothyroidism can cause graying hair

Endocrineweb adds: “Lack of thyroid hormone due to hypothyroidism leads to inflammation and fluid accumulation in the mucous glands, causing them to swell.”

There is evidence that the body may also produce more connective tissue, known as cartilage, inside the nasal cavity.

It is known that in addition to changes in the structure of the nose, a person’s sense of smell suffers.

An early study published in the American Journal of Medicine states that “smell defects are common clinical abnormalities in primary hypothyroidism, suggesting that these defects may contribute to […] the lack of food [is] frequently seen.”

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It is clear that this condition can significantly affect the perception of smell, weakening or even completely suppressing it.

The occurrence of these neurological symptoms must be associated with damage to the nervous system.

The journal BioMed Research International suggests that fluid retention caused by hypothyroidism may be due to pressure on peripheral nerves.

Peripheral neuropathy may develop, which is one of the most likely causes of impaired sense of smell.

READ MORE: Hypothyroidism: Five Warning Signs On Your Nails

“In the worst cases, it can progress to a comatose state, which is obviously to be avoided at all costs.”

Rory Butt, MSc in Personalized Nutrition, explained: “It’s pretty hard to tell what exactly hypothyroidism is behind some of these symptoms until it’s been confirmed with functional testing.

“The tests available on the NHS are not very informative and don’t give the full picture.”

The expert explained that the most prominent symptoms associated with hypothyroidism are fatigue, brain fog, poor memory and concentration.

Correcting any thyroid imbalance is critical, as chronic thyroid hormone deficiency can have dire consequences.

Dr. Claire Thomas, Clinical Content Lead for the wellness app Evergreen life, explained that in the later stages of the disease, a person can suffer from myxedema.

She said: “Another symptom of a more advanced case of hypothyroidism is called myxedema, which causes your face to become swollen and puffy.

“Myxedema is considered severe, so any sign of it, along with these other symptoms, is an indication to see a doctor as soon as possible.

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